Martin K. Safo: search on Z-Library

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1

Hemoglobin–ligand binding: Understanding Hb function and allostery on atomic level

Martin K. Safo, Mostafa H. Ahmed, Mohini S. Ghatge, Telih Boyiri

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2011

Language:

english

File:

PDF, 1.49 MB

english, 2011

2

Structural Basis for the Potent Antisickling Effect of a Novel Class of Five-Membered Heterocyclic Aldehydic Compounds

Safo, Martin K., Abdulmalik, Osheiza, Danso-Danquah, Richmond, Burnett, James C., Nokuri, Samuel, Joshi, Gajanan S., Musayev, Faik N., Asakura, Toshio, Abraham, Donald J.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 969 KB

english, 2004

3

5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells

Osheiza Abdulmalik, Martin K. Safo, Qiukan Chen, Jisheng Yang, Carlo Brugnara, Kwaku Ohene-Frempong, Donald J. Abraham, Toshio Asakura

Journal:

British Journal of Haematology

Year:

2005

Language:

english

File:

PDF, 426 KB

english, 2005

4

Models of the cytochromes b. structural and spectroscopic investigations of low-spin bis-pocket hemins.

F.Ann Walker, Ursula Simonis, Martin K. Safo, W.Robert Scheidt

Journal:

Journal of Inorganic Biochemistry

Year:

1991

Language:

english

File:

PDF, 73 KB

english, 1991

5

Crystallization and Preliminary X-ray Crystallographic Analysis of Pyridoxine 5′-Phosphate Oxidase Complexed with Flavin Mononucleotide

Faik N. Musayev, Martin K. Safo, Martino L. Di Salvo, Verne Schirch, Donald J. Abraham

Journal:

Journal of Structural Biology

Year:

1999

Language:

english

File:

PDF, 112 KB

english, 1999

6

Chlorido(2,3,7,8,12,13,17,18-octaethylporphyrinato)iron(III) dichloromethane sesquisolvate

Safo, Martin K., Buentello, Kristin E., Oliver, Allen G., Scheidt, W. Robert

Journal:

Acta Crystallographica Section E Structure Reports Online

Year:

2010

Language:

english

File:

PDF, 614 KB

english, 2010

7

X-ray crystal structure of a 2-amino-3,4-dihydroquinazoline 5-HT3 serotonin receptor antagonist and related analogs

Abdelkhalek, Ahmed S., Musayev, Faik N., Iyer, Kavita A., Hemanth, Prithvi, Safo, Martin K., Dukat, Małgorzata

Journal:

Journal of Molecular Structure

Year:

2019

Language:

english

File:

PDF, 1.56 MB

english, 2019

8

Identification of a series of tetrahydroisoquinoline derivatives as potential therapeutic agents for breast cancer

Hsiang-Ru Lin, Martin K. Safo, Donald J. Abraham

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 691 KB

english, 2007

9

Bisaldehyde Allosteric Effectors as Molecular Ratchets and Probes

Boyiri, Telih, Safo, Martin K., Danso-Danquah, Richmond E., Kister, Jean, Poyart, Claude, Abraham, Donald J.

Journal:

Year:

1995

Language:

english

File:

PDF, 4.62 MB

english, 1995

10

Models of the Cytochromes. Axial Ligand Orientation and Complex Stability in Iron(II) Porphyrinates: The Case of the Noninteracting d π Orbitals

Safo, Martin K., Nesset, Marlys J. M., Walker, F. Ann, Debrunner, Peter G., Scheidt, W. Robert

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 289 KB

english, 1997

11

The Nitrite Anion Binds to Human Hemoglobin via the Uncommon O -Nitrito Mode †

Yi, Jun, Safo, Martin K., Richter-Addo, George B.

Journal:

Year:

2008

Language:

english

File:

PDF, 304 KB

english, 2008

12

Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease

Xu, Guoyan G., Pagare, Piyusha P., Ghatge, Mohini S., Safo, Ronni P., Gazi, Aheema, Chen, Qiukan, David, Tanya, Alabbas, Alhumaidi B., Musayev, Faik N., Venitz, Jürgen, Zhang, Yan, Safo, Martin K., Ab

Journal:

Molecular Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 3.43 MB

english, 2017

13

Enhancement of Simvastatin ex vivo Permeation from Mucoadhesive Buccal Films Loaded with Dual Drug Release Carriers

Ahmed, Tarek A, Bawazir, Alaa O, Alharbi, Waleed S, Safo, Martin K

Journal:

International Journal of Nanomedicine

Year:

2020

File:

PDF, 4.73 MB

2020

14

Effective and Versatile Synthesis of Ginkgotoxin and Its 4â²-O-Derivatives through Regioselective 4â²-O-Alkylation and 4â²-O-Chlorination of 3,5â²-O-Dibenzylpyridoxine

Huang, Boshi, Danso-Danquah, Richmond, Safo, Martin K., Zhang, Yan

Journal:

Year:

2020

File:

PDF, 497 KB

2020

15

Hb Baden: Structural and functional characterization

Osheiza Abdulmalik, Martin K. Safo, Steven H. Seeholzer, Toshio Asakura, Nicole C. Hasbrouck, J. Eric Russell

Journal:

American Journal of Hematology

Year:

2010

Language:

english

File:

PDF, 342 KB

english, 2010

16

Axial Ligand Orientation in Iron(III) Porphyrinates: Effect of Axial .pi.-Acceptors. Characterization of the Low-Spin Complex [Fe(TPP)(4-CNPy)2]ClO4

Safo, Martin K., Walker, F. Ann, Raitsimring, Arnold M., Walters, W. Patrick, Dolata, Daniel P., Debrunner, Peter G., Scheidt, W. Robert

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 1.29 MB

english, 1994

17

New class of bridged diiron(III) complexes with a single hydroxo bridge. The preparation and structure of (.mu.-hydroxo)bis((octaethylporphinato)iron(III)) perchlorate

Scheidt, W. Robert, Cheng, Beisong, Safo, Martin K., Cukiernik, Fabio, Marchon, Jean Claude, Debrunner, Peter G.

Journal:

Journal of the American Chemical Society

Year:

1992

Language:

english

File:

PDF, 304 KB

english, 1992

18

A Plasmid-Borne System To Assess the Excision and Integration of Staphylococcal Cassette Chromosome mec Mediated by CcrA and CcrB

Wang, Lei, Ahmed, Mostafa H., Safo, Martin K., Archer, Gordon L., Schneewind, O.

Journal:

Journal of Bacteriology

Year:

2015

Language:

english

File:

PDF, 2.63 MB

english, 2015

19

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Prodrugs as Drug Candidates for the Treatment of Ischemic Disorders: Insights into NO-releasing prodrugs biotransformation and hemoglobin-NO biochemistry

Xu, Guoyan G., Deshpande, Tanvi M, Ghatge, Mohini S, Mehta, Akul Y., Omar, Abdel Sattar M., Ahmed, Mostafa H, Venitz, Jurgen, Abdulmalik, Osheiza, Zhang, Yan, Safo, Martin K.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.03 MB

english, 2015

20

Crystal structure of carbonmonoxy sickle hemoglobin in R-state conformation

Ghatge, Mohini S., Ahmed, Mostafa H., Omar, Abdel Sattar M., Pagare, Piyusha P., Rosef, Susan, Kellogg, Glen E., Abdulmalik, Osheiza, Safo, Martin K.

Journal:

Journal of Structural Biology

Year:

2016

Language:

english

File:

PDF, 1.52 MB

english, 2016

21

Crystallization and preliminary X-ray crystallographic analysis of ImmE7 protein of colicin E7

Wen-Yen Ku, Ching-Shao Wang, Chieh-Yen Chen, Kin-Fu Chak, Martin K. Safo, Hanna S. Yuan

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1995

Language:

english

File:

PDF, 314 KB

english, 1995

22

Unintended consequences? Water molecules at biological and crystallographic protein–protein interfaces

Ahmed, Mostafa H., Habtemariam, Mesay, Safo, Martin K., Scarsdale, J. Neel, Spyrakis, Francesca, Cozzini, Pietro, Mozzarelli, Andrea, Kellogg, Glen E.

Journal:

Computational Biology and Chemistry

Year:

2013

Language:

english

File:

PDF, 720 KB

english, 2013

23

Models of cytochromes b. Attempts to control axial ligand orientation with a "hindered" porphyrin system

Hatano, Keiichiro., Safo, Martin K., Walker, F. Ann., Scheidt, W. Robert.

Journal:

Inorganic Chemistry

Year:

1991

Language:

english

File:

PDF, 1.04 MB

english, 1991

24

Structural basis for the antipolymer activity of Hb

Safo, Martin K., Ko, Tzu-Ping, Schreiter, Eric R., Eric Russell, J.

Journal:

Journal of Molecular Structure

Year:

2015

Language:

english

File:

PDF, 1.49 MB

english, 2015

25

Maintaining pH-dependent conformational flexibility of M1 is critical for efficient influenza A virus replication

Chiang, Meng-Jung, Musayev, Faik N, Kosikova, Martina, Lin, Zhengshi, Gao, Yamei, Mosier, Philip D, Althufairi, Bashayer, Ye, Zhiping, Zhou, Qibing, Desai, Umesh R, Xie, Hang, Safo, Martin K

Journal:

Emerging Microbes & Infections

Year:

2017

Language:

english

File:

PDF, 3.52 MB

english, 2017

26

Molecular structure of bis(1-methylimidazole)(meso-tetraphenylporphinato)iron(III) perchlorate

Thomas B. Higgins, Martin K. Safo, W.Robert Scheidt

Journal:

Inorganica Chimica Acta

Year:

1990

Language:

english

File:

PDF, 686 KB

english, 1990

27

Crystal Structure of human pyridoxal kinase: Structural basis of M+ and M2+ activation

Faik N. Musayev, Martino L. di Salvo, Tzu-Ping Ko, Amit K. Gandhi, Ashwini Goswami, Verne Schirch, Martin K. Safo

Journal:

Protein Science

Year:

2007

Language:

english

File:

PDF, 653 KB

english, 2007

28

Synthesis and X-ray Studies of Chiral Allosteric Modifiers of Hemoglobin

Youssef, Amal Mamdouh, Safo, Martin K., Danso-Danquah, Richmond, Joshi, Gajanan S., Kister, Jean, Marden, Michael C., Abraham, Donald J.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 319 KB

english, 2002

29

Inactive mutants of human pyridoxine 5′-phosphate oxidase: a possible role for a noncatalytic pyridoxal 5′-phosphate tight binding site

Ghatge, Mohini S., Karve, Sayali S., David, Tanya M. S., Ahmed, Mostafa H., Musayev, Faik N., Cunningham, Kendra, Schirch, Verne, Safo, Martin K.

Journal:

Year:

2016

Language:

english

File:

PDF, 440 KB

english, 2016

30

Characterization of the mixed axial ligand complex (4-cyanopyridine)(imidazole)(tetramesitylporphinato)iron(iii) perchlorate. Stabilization by synergic bonding

Guzzoa, Judith A., Turowska-Tyrka, Ilona, Safo, Martin K., Walker, F. Ann, Debrunner, Peter G., Scheidt, W. Robert

Journal:

Journal of Porphyrins and Phthalocyanines

Year:

2016

Language:

english

File:

PDF, 491 KB

english, 2016

31

Psiadia punctulata major flavonoids alleviate exaggerated vasoconstriction produced by advanced glycation end products

Abdallah, Hossam M., Zakaria, Esraa M., El-Halawany, Ali M., Mohamed, Gamal A., Safo, Martin K., El-Bassossy, Hany M., Bader, Michael

Journal:

Year:

2019

Language:

english

File:

PDF, 2.97 MB

english, 2019

32

An Investigation of Structure-Activity Relationships of Azolylacryloyl Derivatives Yielded Potent and Long-Acting Hemoglobin Modulators for Reversing Erythrocyte Sickling

Omar, Abdelsattar M., Abdulmalik, Osheiza, Ghatge, Mohini S., Muhammad, Yosra A., Paredes, Steven D., El-Araby, Moustafa E., Safo, Martin K.

Journal:

Year:

2020

File:

PDF, 3.02 MB

2020

33

High–resolution crystal structure of deoxy hemoglobin complexed with a potent allosteric effector

Martin K. Safo, Carmen M. Moure, James C. Burnett, Gajanan S. Joshi, Donald J. Abraham

Journal:

Protein Science

Year:

2001

Language:

english

File:

PDF, 437 KB

english, 2001

34

Synthesis, Structure, and Characterization of Five-Coordinate Aquo(octaethylporphinato)iron(III) Perchlorate

Cheng, Beisong, Safo, Martin K., Orosz, Robert D., Reed, Christopher A., Debrunner, Peter G., Scheidt, W. Robert

Journal:

Inorganic Chemistry

Year:

1994

Language:

english

File:

PDF, 823 KB

english, 1994

35

Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition

Gandhi, Amit K., Desai, Jigar V., Ghatge, Mohini S., di Salvo, Martino L., Di Biase, Stefano, Danso-Danquah, Richmond, Musayev, Faik N., Contestabile, Roberto, Schirch, Verne, Safo, Martin K., Silman,

Journal:

Year:

2012

Language:

english

File:

PDF, 716 KB

english, 2012

36

Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism †

Szebenyi, Doletha M. E., Musayev, Faik N., di Salvo, Martino L., Safo, Martin K., Schirch, Verne

Journal:

Year:

2004

Language:

english

File:

PDF, 474 KB

english, 2004

37

Predicting the molecular interactions of CRIP1a–cannabinoid 1 receptor with integrated molecular modeling approaches

Ahmed, Mostafa H., Kellogg, Glen E., Selley, Dana E., Safo, Martin K., Zhang, Yan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 3.00 MB

english, 2014

38

Broad Spectrum Anti-Influenza Agents by Inhibiting Self-Association of Matrix Protein 1

Mosier, Philip D., Chiang, Meng-Jung, Lin, Zhengshi, Gao, Yamei, Althufairi, Bashayer, Zhou, Qibing, Musayev, Faik, Safo, Martin K., Xie, Hang, Desai, Umesh R.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.54 MB

english, 2016

39

Rational Design of Pyridyl Derivatives of Vanillin for the Treatment of Sickle Cell Disease.

Pagare, Piyusha P., Ghatge, Mohini S., Musayev, Faik N., Deshpande, Tanvi M., Chen, Qiukan, Braxton, Courtney, Kim, Solyi, Venitz, Jürgen, Zhang, Yan, Abdulmalik, Osheiza, Safo., Martin K.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.67 MB

english, 2018

40

Aryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of Hemoglobin

Omar, Abdelsattar, Mahran, Mona, Ghatge, Mohini, Bamane, Faida, Ahmed, Mostafa, El-Araby, Moustafa, Abdulmalik, Osheiza, Safo, Martin

Journal:

Year:

2016

Language:

english

File:

PDF, 3.91 MB

english, 2016

41

The X-ray structure determination of bovine carbonmonoxy hemoglobin at 2.1 Å resoultion and its relationship to the quaternary structures of other hemoglobin crystal forms

Martin K. Safo, Donald J. Abraham

Journal:

Protein Science

Year:

2001

Language:

english

File:

PDF, 679 KB

english, 2001

42

[RSC Drug Discovery] Computational Approaches to Nuclear Receptors || Chapter 2. The Experimental 3D Structure of Nuclear Receptors. A Starting Point for Computational Investigations?

Safo*, Martin K.

Year:

2012

Language:

english

File:

PDF, 479 KB

english, 2012

43

On the catalytic mechanism and stereospecificity of Escherichia coli l -threonine aldolase

di Salvo, Martino L., Remesh, Soumya G., Vivoli, Mirella, Ghatge, Mohini S., Paiardini, Alessandro, D'Aguanno, Simona, Safo, Martin K., Contestabile, Roberto

Journal:

Year:

2014

Language:

english

File:

PDF, 934 KB

english, 2014

44

Rational modification of vanillin derivatives to stereospecifically destabilize sickle hemoglobin polymer formation

Deshpande, Tanvi M., Pagare, Piyusha P., Ghatge, Mohini S., Chen, Qiukan, Musayev, Faik N., Venitz, Jurgen, Zhang, Yan, Abdulmalik, Osheiza, Safo, Martin K.

Journal:

Acta Crystallographica Section D Structural Biology

Year:

2018

Language:

english

File:

PDF, 306 KB

english, 2018

45

Axial ligand orientation in iron(II) porphyrinates. Preparation and characterization of low-spin bis(imidazole)(tetraphenylporphyrinato)iron(II) complexes

Safo, Martin K., Scheidt, W. Robert, Gupta, Govind P.

Journal:

Inorganic Chemistry

Year:

1990

Language:

english

File:

PDF, 1.04 MB

english, 1990

46

Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients

Rab, Minke A.E., van Oirschot, Brigitte A., Bos, Jennifer, Merkx, Tesy H., van Wesel, Annet C.W., Abdulmalik, Osheiza, Safo, Martin K., Versluijs, A. Birgitta, Houwing, Maite E., Cnossen, Marjon H., R

Journal:

American Journal of Hematology

Year:

2019

File:

PDF, 1.73 MB

2019

47

Investigating the Potential of Transmucosal Delivery of Febuxostat from Oral Lyophilized Tablets Loaded with a Self-Nanoemulsifying Delivery System

Al-Amodi, Yasir A., Hosny, Khaled M, Alharbi, Waleed S., Safo, Martin K., El-Say, Khalid M

Journal:

Year:

2020

File:

PDF, 2.49 MB

2020

48

Structure and properties of recombinant human pyridoxine 5′-phosphate oxidase

Faik N. Musayev, Martino L. Di Salvo, Tzu-Ping Ko, Verne Schirch, Martin K. Safo

Journal:

Protein Science

Year:

2003

Language:

english

File:

PDF, 426 KB

english, 2003

49

Crystallographic Trapping of Heme Loss Intermediates during the Nitrite-Induced Degradation of Human Hemoglobin

Yi, Jun, Thomas, Leonard M., Musayev, Faik N., Safo, Martin K., Richter-Addo, George B.

Journal:

Year:

2011

Language:

english

File:

PDF, 3.81 MB

english, 2011

50

The Crystal Structure of the Immunity Protein of Colicin E7 Suggests a Possible Colicin-Interacting Surface

Kin-Fu Chak, Martin K. Safo, Wen-Yen Ku, Shih-Yang Hsieh and Hanna S. Yuan

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.11 MB

english, 1996

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